What Is D-mannose?
D-Mannose is a monosaccharide; a sugar.
D-Mannose & UTIs
A 2014 trial by the World Journal Of Urology found: “D-mannose powder had significantly reduced the risk of recurrent UTIs”.
Another study by the Clinical Journal of Urology concluded: “D-mannose appears to be a safe and effective treatment for recurrent UTIs in adult women”. A “significant difference was observed in the proportion of women remaining infection-free after taking D-mannose versus antibiotic treatment”.
When you take D-mannose, the majority of it is filtered by the kidneys. From the kidneys, it is directed towards the bladder, then excreted from the body via the process of urination.
D-Mannose does not interfere with blood sugar levels. Although technically from the ‘sugar’ family, D mannose does not stimulate an insulin release.
How Does D-Mannose Work?
D-Mannose is covered in microscopic fimbriae. The fimbria enables it to adhere to E. coli bacteria (the most common cause of UTIS).
E. coli bacteria preferentially binds to D-mannose over bladder wall cells. When E. Coli adheres to the cell wall of the bladder, it results in a bladder infection. However, if D mannose is present in the bladder, the E. coli binds with it as opposed to the bladder lining.This adhesion process then sees the D-mannose and E. coli excreted from the body together, via the process of urination.