"Knowledge of D-Mannose’s inhibitive abilities date back to the 1990s, when the influence of D-Mannose on the adhesion of Escherichia coli to human urinary epithelial cells was first investigated."
(Ibwala, Devleeschouwer & Dony, 1990)
A randomised d-mannose clinical trial conducted in 2013 revealed: “D-Mannose powder had significantly reduced the risk of recurrent urinary tract infections.”
(Kranjčec, Papeš and Altarac, 2013)
In 2014, the Journal of Urology recognised D-Mannose’s prophylaxis abilities, stating: “D-Mannose appeared to be a safe and effective treatment for recurrent UTIs in adult women.”
(Porru et al., 2014)
"For the first time, we are seeing common infections, such as urinary tract infections, caused by bacteria such as E.coli, becoming impossible to treat with antibiotics."
(McKenna, J, 2014)